UV-Induced Crosslinking of Poly[2-(2’-Norbornenyl)-2-Oxazoline]s

Convenient one-pot synthesis of 2-oxazolines from carboxylic acids.

Simple one-pot methods for preparation of 2-oxazolines have been developed using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM). Treatment of a mixture of carboxylic acids and 2-haloethylammonium salts with DMT-MM in methanol followed by refluxing in the presence of KOH gives oxazolines.

Synthesis and Analgesic activity of certain 2-Oxazolines

Oxazoline is one of the 5 membered heterocycle ring can be synthesized in many ways and various activities like analgesic, antimicrobial and antidiabetic activity are well documented. In the present study analgesic activity screened by tail flick and tail immersion model.The synthesized compounds are ideally characterized spectrophotometrically. Chlorinated and methoxylated oxazolines found to ...

Biocompatibility and Immunocompatibility Assessment of Poly(2-Oxazolines)

Poly(2-oxazolines) in biological and biomedical application contexts.

Polyoxazolines of various architectures and chemical functionalities can be prepared in a living and therefore controlled manner via cationic ring-opening polymerisation. They have found widespread applications, ranging from coatings to pigment dispersants. Furthermore, several polyoxazolines are water-soluble or amphiphilic and relatively non-toxic, which makes them interesting as biomaterials...

The use of phosphonium anhydrides for the synthesis of 2-oxazolines, 2-thiazolines and 2-dihydrooxazine under mild conditions.

Beta-hydroxy amides 6 and 7 were treated with triphenylphosphonium anhydride trifluoromethane sulfonate (3), or the cyclic analogue 4, to generate 2-oxazolines 5 and 8 under mild conditions. The reaction was optimised by examining the number of equivalents of reagents 3 or 4, or diisopropylethyl amine required to best effect cyclisation. The effects of altering the reaction temperature, reactio...